Bile duct ligation differently regulates protein expressions of organic cation transporters in intestine, liver and kidney of rats through activation of farnesoid X receptor by cholate and bilirubin

• मुख्य लेखकों: Shijin Hong (लेखक), Shuai Li (लेखक), Xiaoyan Meng (लेखक), Ping Li (लेखक), Xun Wang (लेखक), Mengxiang Su (लेखक), Xiaodong Liu (लेखक), Li Liu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Body is equipped with organic cation transporters (OCTs). These OCTs mediate drug transport and are also involved in some disease process. We aimed to investigate whether liver failure alters intestinal, hepatic and renal Oct expressions using bile duct ligation (BDL) rats. Pharmacokinetic analysis...