Development and validation of small animal models for onchocerciasis and loiasis microfilaricide discovery.

• Main Authors: Rene Bilingwe Ayiseh (Author), Glory Enjong Mbah (Author), Elvis Monya (Author), Emmanuel Menang Ndi (Author), Judy Sakanari (Author), Sara Lustigman (Author), Fidelis Cho-Ngwa (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Onchocerciasis (river blindness) caused by the filarial worm Onchocerca volvulus is a neglected tropical disease that affects the skin and eyes of humans. Mass drug administration with ivermectin (IVM) to control the disease often suffers from severe adverse events in...