PTC596-Induced BMI-1 Inhibition Fights Neuroblastoma Multidrug Resistance by Inducing Ferroptosis

• المؤلفون الرئيسيون: Giulia Elda Valenti (مؤلف), Antonella Roveri (مؤلف), Rina Venerando (مؤلف), Paola Menichini (مؤلف), Paola Monti (مؤلف), Bruno Tasso (مؤلف), Nicola Traverso (مؤلف), Cinzia Domenicotti (مؤلف), Barbara Marengo (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2023-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Neuroblastoma (NB) is a paediatric cancer with noteworthy heterogeneity ranging from spontaneous regression to high-risk forms that are characterised by cancer relapse and the acquisition of drug resistance. The most-used anticancer drugs exert their cytotoxic effect by inducing oxidative stress, an...