Endogenous progesterone levels and frontotemporal dementia: modulation of TDP-43 and Tau levels in vitro and treatment of the A315T TARDBP mouse model

• Main Authors: Theresa N. T. Dang (Author), Carol Dobson-Stone (Author), Elias N. Glaros (Author), Woojin S. Kim (Author), Marianne Hallupp (Author), Lauren Bartley (Author), Olivier Piguet (Author), John R. Hodges (Author), Glenda M. Halliday (Author), Kay L. Double (Author), Peter R. Schofield (Author), Peter J. Crouch (Author), John B. J. Kwok (Author)
• Format: Book
• Published: The Company of Biologists, 2013-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Frontotemporal dementia (FTD) is associated with motor neurone disease (FTD-MND), corticobasal syndrome (CBS) and progressive supranuclear palsy syndrome (PSPS). Together, this group of disorders constitutes a major cause of young-onset dementia. One of the three clinical variants of FTD is...