Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cells

Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cells

Abstract Background Breast cancer is a prevalent malignant tumor that affects women worldwide. The primary challenge in treating breast cancer is combating drug resistance, which contributes to relapse and metastasis. Jatrophone is a unique macrocyclic jatrophane diterpene found in various Jatropha...

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Main Authors: Khawlah Shari (Author), Rania A. El Gedaily (Author), Rasha M. Allam (Author), Khaled M. Meselhy (Author), Amal E. Khaleel (Author), Essam Abdel-Sattar (Author)
Format: Book
Published: BMC, 2023-08-01T00:00:00Z.
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3rd Floor Main Library

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