Detection of PNH cells by flow cytometry, using multiparameter analysis

• Main Authors: Juliana Maria Camargos Rocha (Author), Maria Luíza Silva (Author), Marcelo Eduardo de Lima Souza (Author), Mitiko Murao (Author), Sérgio Schusterschitz da Silva Araújo (Author), Silvana Maria Elói Santos (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction:The laboratory diagnosis of paroxysmal nocturnal hemoglobinuria (PNH), disease that is categorized by reduced synthesis of glycosylphosphatidylinositol (GPI) anchor, is based on the detection of blood cells deficient in GPI-anchored proteins by flow cytometry. PNH clones have been detec...