Progranulin Inhibits Human T Lymphocyte Proliferation by Inducing the Formation of Regulatory T Lymphocytes

We have examined the effect of progranulin (PGRN) on human T cell proliferation and its underlying mechanism. We show that PGRN inhibits the PHA-induced multiplication of T lymphocytes. It increases the number of iTregs when T lymphocytes are activated by PHA but does not do so in the absence of PHA...

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Bibliographic Details
Main Authors: Kyu Hwan Kwack (Author), Hyeon-Woo Lee (Author)
Format: Book
Published: Hindawi Limited, 2017-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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