Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice

• Main Authors: Tomoyo Kawakubo-Yasukochi (Author), Ena Yano (Author), Soi Kimura (Author), Takuya Nishinakagawa (Author), Akiko Mizokami (Author), Yoshikazu Hayashi (Author), Yuji Hatakeyama (Author), Kenji Ohe (Author), Atsushi Yasukochi (Author), Seiji Nakamura (Author), Eijiro Jimi (Author), Masato Hirata (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Accumulating evidence indicates that an adverse perinatal environment contributes to a higher risk of metabolic disorders in the later life of the offspring. However, the underlying molecular mechanisms remain largely unknown. Thus, we investigated the contribution of maternal high-calori...