Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus Slices

• Autori principali: Tomoko Hyakumura (Autore), Stuart McDougall (Autore), Sue Finch (Autore), Karina Needham (Autore), Mirella Dottori (Autore), Bryony A. Nayagam (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2019-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Stem cells have been touted as a source of potential replacement neurons for inner ear degeneration for almost two decades now; yet to date, there are few studies describing the use of human pluripotent stem cells (hPSCs) for this purpose. If stem cell therapies are to be used clinically, it is crit...