Role and action mechanisms of tPA in CRH-induced apoptosis of mouse oviductal epithelial and mural granulosa cells

• Main Authors: Yong-Qing YANG (Author), Min ZHANG (Author), Qi HUA (Author), Rui-Jie MA (Author), Xiao-Yan WANG (Author), Hong-Jie YUAN (Author), Ming-Jiu LUO (Author), Jing-He TAN (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Understanding how stress hormones induce apoptosis in oviductal epithelial cells (OECs) and mural granulosa cells (MGCs) can reveal the mechanisms by which female stress impairs embryonic development and oocyte competence. A recent study showed that tissue plasminogen activator (tPA) ameliorates cor...