On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development
A small-scale biphasic dissolution setup and a small-scale dissolution-permeation (D-P) setup were evaluated for their usefulness in simulating the luminal precipitation of three lipophilic weak bases—dipyridamole, ketoconazole and itraconazole. The transition from the gastric to intestina...
Saved in:
Main Authors: | Patrick J. O'Dwyer (Author), Georgios Imanidis (Author), Karl J. Box (Author), Christos Reppas (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2020-03-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Optimization of self-nanoemulsifying formulations for weakly basic lipophilic drugs: role of acidification and experimental design
by: Ahmad Abdul-Wahhab Shahba, et al. -
Biorelevant drug release of Metformin dosage forms using complementary in vitro tools
by: Karl Box, et al.
Published: (2017) -
A composite nanocarrier to inhibit precipitation of the weakly basic drug in the gastrointestinal tract
by: Chunli Zheng, et al.
Published: (2020) -
Characterizing the Physicochemical Properties of Two Weakly Basic Drugs and the Precipitates Obtained from Biorelevant Media
by: Miao Zhang, et al.
Published: (2022) -
The Luminous Face
by: Wells, Carolyn, 1862-1942