Role of M1 macrophages in diabetic foot ulcers and related immune regulatory mechanisms

• Main Authors: Yao Li (Author), Xiaoyan Li (Author), Shuai Ju (Author), Wenqiang Li (Author), Siyuan Zhou (Author), Guili Wang (Author), Yunmin Cai (Author), Zhihui Dong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Diabetes foot ulcers (DFUs) are characterized by immune infiltration of M1 macrophages observed in foot skin, in which immune-associated genes (IRGs) play a prominent role. The precise expression of IRGs as well as any possible regulatory mechanisms that could be present in DFUs is yet u...