Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation

• Main Authors: Ewelina Dobosz (Author), Georg Lorenz (Author), Andrea Ribeiro (Author), Vivian Würf (Author), Marta Wadowska (Author), Jerzy Kotlinowski (Author), Christoph Schmaderer (Author), Jan Potempa (Author), Mingui Fu (Author), Joanna Koziel (Author), Maciej Lech (Author)
• Format: Book
• Published: The Company of Biologists, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myeloid-derived cells, in particular macrophages, are increasingly recognized as critical regulators of the balance of immunity and tolerance. However, whether they initiate autoimmune disease or perpetuate disease progression in terms of epiphenomena remains undefined. Here, we show that depletion...