Newborn Screening for Severe Combined Immunodeficiency Using the Multiple of the Median Values of T-Cell Receptor Excision Circles

• Main Authors: Michael F. Cogley (Author), Amy E. Wiberley-Bradford (Author), Sean T. Mochal (Author), Sandra J. Dawe (Author), Zachary D. Piro (Author), Mei W. Baker (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2021-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

All newborn screening programs screen for severe combined immunodeficiency by measurement of T-cell receptor excision circles (TRECs). Herein, we report our experience of reporting TREC assay results as multiple of the median (MoM) rather than using conventional copy numbers. This modification simpl...