Muscle‐specific functional deficits and lifelong fibrosis in response to paediatric radiotherapy and tumour elimination

• Main Authors: Jacob G. Kallenbach (Author), John F. Bachman (Author), Nicole D. Paris (Author), Roméo S. Blanc (Author), Thomas O'Connor (Author), Esraa Furati (Author), Eric Hernady (Author), Carl J. Johnston (Author), Jacqueline P. Williams (Author), Joe V. Chakkalakal (Author)
• Format: Book
• Published: Wiley, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background As paediatric cancer survivors are living into adulthood, they suffer from the age‐related, accelerated decline of functional skeletal muscle tissue, termed sarcopenia. With ionizing radiation (radiotherapy) at the core of paediatric cancer therapies, its direct and indirect effe...