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Endometrial stromal sarcomas with BCOR‐rearrangement harbor MDM2 amplifications

Abstract Recently a novel subtype of endometrial stromal sarcoma (ESS) defined by recurrent genomic alterations involving BCOR has been described (HGESS‐BCOR). We identified a case of HGESS‐BCOR with a ZC3H7B‐BCOR gene fusion, which harbored an amplification of the MDM2 locus. This index case prompt...

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Main Authors: Felix KF Kommoss (Author), Kenneth TE Chang (Author), Damian Stichel (Author), Ana Banito (Author), David TW Jones (Author), Christoph E Heilig (Author), Stefan Fröhling (Author), Felix Sahm (Author), Albrecht Stenzinger (Author), Wolfgang Hartmann (Author), Gunhild Mechtersheimer (Author), Hans‐Peter Sinn (Author), Dietmar Schmidt (Author), Friedrich Kommoss (Author), Andreas vonDeimling (Author), Christian Koelsche (Author)
Format: Book
Published: Wiley, 2020-07-01T00:00:00Z.
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