Transcriptomic analysis of N-terminal mutated Trypanosoma cruzi UBP1 knockdown underlines the importance of this RNA-binding protein in parasite development.

• Κύριοι συγγραφείς: Karina B Sabalette (Συγγραφέας), Vanina A Campo (Συγγραφέας), José R Sotelo-Silveira (Συγγραφέας), Pablo Smircich (Συγγραφέας), Javier G De Gaudenzi (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Public Library of Science (PLoS), 2024-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

<h4>Background</h4>During its life cycle, the human pathogen Trypanosoma cruzi must quickly adapt to different environments, in which the variation in the gene expression of the regulatory U-rich RNA-binding protein 1 (TcUBP1) plays a crucial role. We have previously demonstrated that th...