Transcriptomic analysis of N-terminal mutated Trypanosoma cruzi UBP1 knockdown underlines the importance of this RNA-binding protein in parasite development.

• Main Authors: Karina B Sabalette (Author), Vanina A Campo (Author), José R Sotelo-Silveira (Author), Pablo Smircich (Author), Javier G De Gaudenzi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>During its life cycle, the human pathogen Trypanosoma cruzi must quickly adapt to different environments, in which the variation in the gene expression of the regulatory U-rich RNA-binding protein 1 (TcUBP1) plays a crucial role. We have previously demonstrated that th...