Sensitive Detection of Pharmaceutical Drugs and Metabolites in Serum Using Data-Independent Acquisition Mass Spectrometry and Open-Access Data Acquisition Tools

• Main Authors: Syed Muhammad Zaki Shah (Author), Arslan Ali (Author), Muhammad Noman Khan (Author), Adeeba Khadim (Author), Mufarreh Asmari (Author), Jalal Uddin (Author), Syed Ghulam Musharraf (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Data-independent acquisition (DIA) based strategies have been explored in recent years for improving quantitative analysis of metabolites. However, the data analysis is challenging for DIA methods as the resulting spectra are highly multiplexed. Thus, the DIA mode requires advanced software analysis...