Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization

• Main Authors: Takahito Nakama (Author), Shigeo Yoshida (Author), Keijiro Ishikawa (Author), Yuki Kubo (Author), Yoshiyuki Kobayashi (Author), Yedi Zhou (Author), Shintaro Nakao (Author), Toshio Hisatomi (Author), Yasuhiro Ikeda (Author), Kazumasa Takao (Author), Kazunori Yoshikawa (Author), Akira Matsuda (Author), Junya Ono (Author), Shoichiro Ohta (Author), Kenji Izuhara (Author), Akira Kudo (Author), Koh-hei Sonoda (Author), Tatsuro Ishibashi (Author)
• Format: Book
• Published: Elsevier, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Retinal neovascularization (NV) due to retinal ischemia remains one of the principal causes of vision impairment in patients with ischemic retinal diseases. We recently reported that periostin (POSTN) may play a role in the development of preretinal fibrovascular membranes, but its role in retinal N...