CYP2D6 in the Brain: Potential Impact on Adverse Drug Reactions in the Central Nervous System-Results From the ADRED Study

• मुख्य लेखकों: Katja S. Just (लेखक), Harald Dormann (लेखक), Mathias Freitag (लेखक), Marlen Schurig (लेखक), Miriam Böhme (लेखक), Michael Steffens (लेखक), Catharina Scholl (लेखक), Thomas Seufferlein (लेखक), Ingo Graeff (लेखक), Matthias Schwab (लेखक), Julia C. Stingl (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cytochrome P450 (CYP) 2D6 is a polymorphic enzyme expressed in the central nervous system (CNS), important in drug metabolism and with a potentially constitutive role in CNS function such as vigilance. This study aimed to analyze variability in CYP2D6 activity linked to vigilance-related adverse dru...