Synthesis of Nitric Oxide Donors Derived from Piloty's Acid and Study of Their Effects on Dopamine Secretion from PC12 Cells

• Main Authors: Daniele Sanna (Author), Gaia Rocchitta (Author), Maria Serra (Author), Marcello Abbondio (Author), Pier Andrea Serra (Author), Rossana Migheli (Author), Lidia De Luca (Author), Eugenio Garribba (Author), Andrea Porcheddu (Author)
• Format: Book
• Published: MDPI AG, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigated the mechanisms and kinetics of nitric oxide (NO) generation by derivatives of Piloty's acid (NO-donors) under physiological conditions. In order to qualitatively and quantitatively measure NO release, electron paramagnetic resonance (EPR) was carried out with NO spin tra...