Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population

• প্রধান লেখক: Line Skute Bråten (লেখক), Magnus Ingelman‐Sundberg (লেখক), Marin M. Jukic (লেখক), Espen Molden (লেখক), Marianne Kristiansen Kringen (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2022-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Sertraline is a commonly used SSRI antidepressant drug, metabolized by CYP2C19 and CYP2B6, that exhibits a substantial interindividual variation in clinical response, of which only a part can be attributed to known genetic variants. In the current study we have examined the role of a newly...