Discovery of Icotinib-1,2,3-Triazole Derivatives as IDO1 Inhibitors

• Hlavní autoři: Long-fei Mao (Autor), Yu-wei Wang (Autor), Jie Zhao (Autor), Gui-qing Xu (Autor), Xiao-jun Yao (Autor), Yue-Ming Li (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Tumor immunotherapy is considered to be a highlight in cancer treatment in recent years. Indoleamine 2,3-dioxygenase 1 (IDO1) is closely related to the over expression of many cancers, and is therefore a promising target for tumor immunotherapy. To search for novel IDO1-targeting therapeutic agents,...