Delivery of therapeutic small interfering RNA: The current patent-based landscape

• Main Authors: Yu Chen (Author), Shi-Hang Xiong (Author), Fei Li (Author), Xiang-Jun Kong (Author), De-Fang Ouyang (Author), Ying Zheng (Author), Hua Yu (Author), Yuan-Jia Hu (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Implementing small interfering RNA (siRNA) is a promising therapy because it silences disease-related genes theoretically. However, the efficient delivery of siRNA is challenging, which limits its therapeutic applications. Various pharmaceutical delivery systems containing key technologies have been...