Nitric Oxide Is the Cause of Nitroglycerin Tolerance: Providing an Old Dog New Tricks for Acute Heart Failure

• Main Authors: Wayne Kaesemeyer MD (Author), Tatsiana Suvorava PhD (Author)
• 格式: 圖書
• 出版: SAGE Publishing, 2022-03-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Our paper highlights the past 50 years of research focusing solely on tolerance involving nitroglycerin (glyceryl trinitrate, GTN). It also identifies and discusses inconsistencies in previous mechanistic explanations that have failed to provide a way to administer GTN continuously, free of limitati...