Novel Diagnostic and Therapeutic Options for KMT2A-Rearranged Acute Leukemias

Novel Diagnostic and Therapeutic Options for KMT2A-Rearranged Acute Leukemias

The KMT2A (MLL) gene rearrangements (KMT2A-r) are associated with a diverse spectrum of acute leukemias. Although most KMT2A-r are restricted to nine partner genes, we have recently revealed that KMT2A-USP2 fusions are often missed during FISH screening of these genetic alterations. Therefore, compl...

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Main Authors: Bruno A. Lopes (Author), Caroline Pires Poubel (Author), Cristiane Esteves Teixeira (Author), Aurélie Caye-Eude (Author), Hélène Cavé (Author), Claus Meyer (Author), Rolf Marschalek (Author), Mariana Boroni (Author), Mariana Emerenciano (Author)
Format: Book
Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
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