DRD4 Mitigates Myocardial Ischemia/Reperfusion Injury in Association With PI3K/AKT Mediated Glucose Metabolism

• Main Authors: Xue-song Liu (Author), Jing Zeng (Author), Yu-xue Yang (Author), Chun-lei Qi (Author), Ting Xiong (Author), Geng-ze Wu (Author), Chun-yu Zeng (Author), Da-xin Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ischemia-reperfusion (I/R) could cause heart irreversible damage, which is tightly combined with glucose metabolism disorder. It is demonstrated that GLUT4 (glucose transporter 4) translocation is critical for glucose metabolism in the cardiomyocytes under I/R injury. Moreover, DRD4 (dopamine recept...