An integrated analysis of public genomic data unveils a possible functional mechanism of psoriasis risk via a long-range ERRFI1 enhancer

• Κύριοι συγγραφείς: Naoto Kubota (Συγγραφέας), Mikita Suyama (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2020-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background Psoriasis is a chronic inflammatory skin disease, for which genome-wide association studies (GWAS) have identified many genetic variants as risk markers. However, the details of underlying molecular mechanisms, especially which variants are functional, are poorly understood. Meth...