Modulation of the Cytotoxic Properties of Pd(II) Complexes Based on Functionalized Carboxamides Featuring Labile Phosphoryl Coordination Sites

• Main Authors: Diana V. Aleksanyan (Author), Aleksandr V. Konovalov (Author), Svetlana G. Churusova (Author), Ekaterina Yu. Rybalkina (Author), Alexander S. Peregudov (Author), Svetlana A. Aksenova (Author), Evgenii I. Gutsul (Author), Zinaida S. Klemenkova (Author), Vladimir A. Kozlov (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Platinum-based drugs are commonly recognized as a keystone in modern cancer chemotherapy. However, intrinsic and acquired resistance as well as serious side effects often caused by the traditional Pt(II) anticancer agents prompt a continuous search for more selective and efficient alternatives. Toda...