Epithelial Dual Oxidase 2 Shapes the Mucosal Microbiome and Contributes to Inflammatory Susceptibility

• প্রধান লেখক: Juan Camilo Castrillón-Betancur (লেখক), Víctor Alonso López-Agudelo (লেখক), Nina Sommer (লেখক), Sven Cleeves (লেখক), Joana Pimenta Bernardes (লেখক), Saskia Weber-Stiehl (লেখক), Philip Rosenstiel (লেখক), Felix Sommer (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2023-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Reactive oxygen species (ROS) are highly reactive molecules formed from diatomic oxygen. They act as cellular signals, exert antibiotic activity towards invading microorganisms, but can also damage host cells. Dual oxidase 2 (DUOX2) is the main ROS-producing enzyme in the intestine, regulated by cue...