Exome, transcriptome and miRNA analysis don't reveal any molecular markers of TKI efficacy in primary CML patients

Exome, transcriptome and miRNA analysis don't reveal any molecular markers of TKI efficacy in primary CML patients

Abstract Background Approximately 5-20% of chronic myeloid leukemia (CML) patients demonstrate primary resistance or intolerance to imatinib. None of the existing predictive scores gives a good prognosis of TKI efficacy. Gene polymorphisms, expression and microRNAs are known to be involved in the pa...

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Main Authors: Alexander V. Lavrov (Author), Ekaterina Yu. Chelysheva (Author), Elmira P. Adilgereeva (Author), Oleg A. Shukhov (Author), Svetlana A. Smirnikhina (Author), Konstantin S. Kochergin-Nikitsky (Author), Valentina D. Yakushina (Author), Grigory A. Tsaur (Author), Sergey V. Mordanov (Author), Anna G. Turkina (Author), Sergey I. Kutsev (Author)
Format: Book
Published: BMC, 2019-03-01T00:00:00Z.
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