The effect of Amine modification on siRNA delivery of redox-responsive PEGylated amphiphilic micellar nanoparticles for triple negative breast cancer therapy

We developed a set of methoxypoly (ethyleneglycol)-co-poly(N3-ε-caprolactone) (mPEG-N3PCL)copolymers with different types of amine linkers and investigated the contribution of the introduced amino linker to the gene delivery efficiency of nanoparticles. The nanoparticles were crosslinked from the ca...

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Main Authors: Fatemeh Mehradnia (Author), Cameron Alexander (Author)
Format: Book
Published: University of Huddersfield Press, 2022-11-01T00:00:00Z.
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3rd Floor Main Library

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