Nanocarrier-mediated co-delivery of chemotherapeutic drugs and gene agents for cancer treatment

• المؤلفون الرئيسيون: Lin Kang (مؤلف), Zhonggao Gao (مؤلف), Wei Huang (مؤلف), Mingji Jin (مؤلف), Qiming Wang (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2015-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The efficacy of chemotherapeutic drug in cancer treatment is often hampered by drug resistance of tumor cells, which is usually caused by abnormal gene expression. RNA interference mediated by siRNA and miRNA can selectively knock down the carcinogenic genes by targeting specific mRNAs. Therefore, c...