Growth Differentiation Factor-15 Correlates Inversely with Protease-Activated Receptor-1-Mediated Platelet Reactivity in Patients with Left Ventricular Assist Devices

• Main Authors: Maximilian Tscharre (Author), Franziska Wittmann (Author), Daniela Kitzmantl (Author), Silvia Lee (Author), Beate Eichelberger (Author), Patricia P. Wadowski (Author), Günther Laufer (Author), Dominik Wiedemann (Author), Simon Panzer (Author), Thomas Perkmann (Author), Daniel Zimpfer (Author), Thomas Gremmel (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Growth differentiation factor (GDF)-15 inhibits platelet activation, prevents thrombus formation, and has been linked to bleeding events. This was a prospective study including 51 left-ventricular assist device (LVAD) patients on aspirin and phenprocoumon. Platelet surface expression of activated gl...