Combining immunoprofiling with machine learning to assess the effects of adjuvant formulation on human vaccine-induced immunity

• Main Authors: Sidhartha Chaudhury (Author), Elizabeth H. Duncan (Author), Tanmaya Atre (Author), Sheetij Dutta (Author), Michele D. Spring (Author), Wolfgang W. Leitner (Author), Elke S. Bergmann-Leitner (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adjuvants produce complex, but often subtle, effects on vaccine-induced immune responses that, nonetheless, play a critical role in vaccine efficacy. In-depth profiling of vaccine-induced cytokine, cellular, and antibody responses ("immunoprofiling") combined with machine-learning holds th...