A physiologically-oriented mathematical model for the description of in vivo drug release and absorption

• Main Authors: Renzo Del Cont (Author), Michela Abrami (Author), Dritan Hasa (Author), Beatrice Perissutti (Author), Dario Voinovich (Author), Anna Barba (Author), Gaetano Lamberti (Author), Gabriele Grassi (Author), Italo Colombo (Author), Davide Manca (Author), Mario Grassi (Author)
• Format: Book
• Published: International Association of Physical Chemists (IAPC), 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This paper focuses on a physiologically-oriented mathematical model aimed at studying the in vivo drug release, absorption, distribution, metabolism and elimination (ADME). To this purpose, the model accounts for drug delivery from an ensemble of non-eroding poly-disperse polymeric particles and the...