Down-Regulation of Tristetraprolin Expression Results in Enhanced IL-12 and MIP-2 Production and Reduced MIP-3α Synthesis in Activated Macrophages

• Autori principali: Ulla Jalonen (Autore), Riina Nieminen (Autore), Katriina Vuolteenaho (Autore), Hannu Kankaanranta (Autore), Eeva Moilanen (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 2006-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

In inflammation, the post-transcriptional regulation of transiently expressed genes provides a potential therapeutic target. Tristetraprolin (TTP) is of the factors regulating decay of cytokine mRNAs. The aim of the present study was to identify cytokines whose expression is regulated by TTP. We est...