Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets
Malignant gliomas are aggressive brain tumors with limited therapeutic options, possibly because of highly tumorigenic subpopulations of glioma stem cells. These cells require specific microenvironments to maintain their "stemness," described as perivascular and hypoxic niches. Each of tho...
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Hindawi Limited,
2016-01-01T00:00:00Z.
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