Intra-articular injection PLGA blends sustained-release microspheres loaded with meloxicam: preparation, optimization, evaluation in vitro and in vivo

• Những tác giả chính: Zheng Sun (Tác giả), Xuejing Gu (Tác giả), Teng Hao (Tác giả), Jiali Liu (Tác giả), Rongrong Gao (Tác giả), Yanli Li (Tác giả), Bin Yu (Tác giả), Hui Xu (Tác giả)
• Định dạng: Sách
• Được phát hành: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Meloxicam (MLX) is a commonly used drug in the clinical treatment of osteoarthritis, but it is associated with gastrointestinal adverse reactions. Therefore, in this study, we developed a sustained-release microsphere formulation of MLX for topical administration of knee joint. The MLX-loaded PLGA m...