The Synergistic Effects of Sulfated Lactosyl Archaeol Archaeosomes When Combined with Different Adjuvants in a Murine Model

• Main Authors: Yimei Jia (Author), Bassel Akache (Author), Gerard Agbayani (Author), Vandana Chandan (Author), Renu Dudani (Author), Blair A. Harrison (Author), Lise Deschatelets (Author), Usha D. Hemraz (Author), Edmond Lam (Author), Sophie Régnier (Author), Felicity C. Stark (Author), Lakshmi Krishnan (Author), Michael J. McCluskie (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Archaeosomes, composed of sulfated lactosyl archaeol (SLA) glycolipids, have been proven to be an effective vaccine adjuvant in multiple preclinical models of infectious disease or cancer. SLA archaeosomes are a promising adjuvant candidate due to their ability to strongly stimulate both humoral and...