Efficient shRNA-based knockdown of multiple target genes for cell therapy using a chimeric miRNA cluster platform
Genome engineering technologies are powerful tools in cell-based immunotherapy to optimize or fine-tune cell functionalities. However, their use for multiple gene edits poses relevant biological and technical challenges. Short hairpin RNA (shRNA)-based cell engineering bypasses these criticalities a...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2023-12-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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