Neuropathic Injury-Induced Plasticity of GABAergic System in Peripheral Sensory Ganglia

• Main Authors: Caixue Wang (Author), Han Hao (Author), Kaitong He (Author), Yating An (Author), Zeyao Pu (Author), Nikita Gamper (Author), Hailin Zhang (Author), Xiaona Du (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

GABA is a major inhibitory neurotransmitter in the mammalian central nervous system (CNS). Inhibitory GABAA channel circuits in the dorsal spinal cord are the gatekeepers of the nociceptive input from the periphery to the CNS. Weakening of these spinal inhibitory mechanisms is a hallmark of chronic...