A HUMANIZED CLINICALLY CALIBRATED QUANTITATIVE SYSTEMS PHARMACOLOGY MODEL FOR HYPOKINETIC MOTOR SYMPTOMS IN PARKINSON'S DISEASE

• Principais autores: Hugo eGeerts (Autor), Patrick eRoberts (Autor), Athan eSpiros (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2016-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The current treatment of Parkinson's disease with dopamine-centric approaches such as L-DOPA and dopamine agonists, although very succesfull, is in need of alternative treatment strategies, both in terms of disease modification and symptom management. Various non-dopaminergic treatment approach...