Human Monocytes Exposed to SARS-CoV-2 Display Features of Innate Immune Memory Producing High Levels of CXCL10 upon Restimulation

• Main Authors: Jelena Cvetkovic (Author), Ronald H.J. Jacobi (Author), Alberto Miranda-Bedate (Author), Nhung Pham (Author), Martina Kutmon (Author), James Groot (Author), Martijn D.B. van de Garde (Author), Elena Pinelli (Author)
• Format: Book
• Published: Karger Publishers, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: A role for innate immune memory in protection during COVID-19 infection or vaccination has been recently reported. However, no study so far has shown whether the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can train innate immune cells. The aim of this study was to inv...