Preclinical Absorption, Distribution, Metabolism, and Excretion of Sodium Danshensu, One of the Main Water-Soluble Ingredients in Salvia miltiorrhiza, in Rats

• Главные авторы: Xiangguo Meng (Автор), Jingjing Jiang (Автор), Hui Pan (Автор), Shengyuan Wu (Автор), Shuowen Wang (Автор), Yuefen Lou (Автор), Guorong Fan (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

In this study, the absorption, distribution, metabolism and excretion (ADME) of sodium danshensu (Sodium DL-β-(3, 4-dihydroxyphenyl)lactate), one of the main water-soluble active constituents in Salvia miltiorrhiza, were evaluated in rats. Pharmacokinetic study was evaluated in doses of 15, 30, and...