Contribution of Histamine to Nociceptive Behaviors Induced by Intrathecally Administered Cholecystokinin-8

• Main Authors: Takafumi Hayashi (Author), Chizuko Watanabe (Author), Soh Katsuyama (Author), Yasuyuki Agatsuma (Author), Damiana Scuteri (Author), Giacinto Bagetta (Author), Tsukasa Sakurada (Author), Shinobu Sakurada (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The involvement of spinal release of histamine in the nociceptive behaviors induced by cholecystokinin-8 (CCK-8) was investigated in mice. Intrathecal (i.t.) injection of CCK-8 elicited the nociceptive behaviors consisting of biting and licking. The nociceptive behaviors induced by i.t. treatment wi...