Direct administration of mesenchymal stem cell‐derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence

• Main Authors: Xiaoting Liang (Author), Yuelin Zhang (Author), Fang Lin (Author), Mimi Li (Author), Xin Li (Author), Yu Chen (Author), Jing Liu (Author), Qingshu Meng (Author), Xiaoxue Ma (Author), Enhao Wang (Author), Lu Wei (Author), Zhiying He (Author), Huimin Fan (Author), Xiaohui Zhou (Author), Yue Ding (Author), Zhongmin Liu (Author)
• Format: Book
• Published: Wiley, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Mitochondrial dysfunction is considered to be a key contributor to the development of heart failure. Replacing injured mitochondria with healthy mitochondria to restore mitochondrial bioenergy in myocardium holds great promise for cardioprotection after infarction. This study aimed to inves...