A targeted covalent inhibitor of p97 with proteome-wide selectivity

A resurging interest in targeted covalent inhibitors (TCIs) focus on compounds capable of irreversibly reacting with nucleophilic amino acids in a druggable target. p97 is an emerging protein target for cancer therapy, viral infections and neurodegenerative diseases. Extensive efforts were devoted t...

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Main Authors: Zi Ye (Author), Ke Wang (Author), Lianguo Chen (Author), Xiaofeng Jin (Author), Hao Chen (Author), Guanghui Tang (Author), Shao Q. Yao (Author), Zhiqiang Feng (Author), Chong-Jing Zhang (Author)
Format: Book
Published: Elsevier, 2022-02-01T00:00:00Z.
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Call Number: A1234.567
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