In silico discovery of repetitive elements as key sequence determinants of 3D genome folding
Summary: Natural and experimental genetic variants can modify DNA loops and insulating boundaries to tune transcription, but it is unknown how sequence perturbations affect chromatin organization genome wide. We developed a deep-learning strategy to quantify the effect of any insertion, deletion, or...
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Elsevier,
2023-10-01T00:00:00Z.
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A1234.567 |
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| Kopie 1 | Beschikbaar |