Possibilities of investigating intratumoral lymphocyte subpopulations by flow cytometry of tumor core biopsy specimens in patients with breast cancer

• Main Authors: F. A. Shamilov (Author), Ya. V. Vishnevskaya (Author), V. Yu. Selchuk (Author), E. M. Pogodina (Author), D. I. Zernov (Author), N. V. Chkhikvadze (Author), V. V. Timoshenko (Author), D. A. Ryabchikov (Author), N. N. Tupitsyn (Author)
• Format: Book
• Published: ABV-press, 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Study of tumor-infiltrating lymphocyte subpopulations was performed in 19 patients with breast cancer (core biopsy material). Two probes were used in multiparameter flow cytometry: CD4/CD25/CD3/CD45 and CD8/CD56/CD3/CD45. Mean percentage of different cell types within lymphocytes (CD45++ SSCLow) was...